The subtle symptoms of chronic mild depression, called dysthymia, may be so woven into people's lives they will be unaware that they have a mental health problem. When being irritable, uninterested in life or feeling miserable goes on for years, they begin to think it's just their nature. Often it isn't. Now a report in the American Journal of Psychiatry adds to the evidence that antidepressants offer some relief, even for people who have had symptoms for 30 years or more. Doctors at eight university medical centers treated more than 400 patients with either Zoloft or Tofranil. Patients ranged in age from 25 to 65, and their symptoms started about age 12, on average. After 12 weeks of treatment, about half of the patients achieved complete remission. They saw improvements in family relationships, social and work life, and the overall quality of their lives. Prozac has also been ef...
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